Biological activities of limonoids in the Genus Khaya (Meliaceae): a review

Abstract Background Limonoids are a class of highly oxygenated modified triterpenoids with diverse range biological activities. Although restricted occurrence in the plant kingdom, these compounds found extensively Meliaceae and Rutaceae families. great interest science given that small number families where they occur exhibit broad medicinal properties promote health prevent disease. Main text The family includes genus Khaya comprises tree species have been used traditional medicine to treat several ailments. In recent years, has attracted much research owing presence limonoids different parts few can serve as therapeutic molecules pharmaceutical industry. this study, literature search over past two decades (2000–2020) was conducted on activities using databases such Google Scholar, PubMed, Scopus ISI Web Science. taxonomy, geographical distribution various uses presented detail. This study reveals currently documented both vivo vitro limited four ( K . anthotheca , grandifoliola ivorensis senegalensis ) include anticancer, antimalarial, hepatoprotection, anti-inflammatory, neuroprotection, antimicrobial, antifungal antifeedant. most well-researched species, notable Conclusion present detailed up-to-date review potentials for drug development managing